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Comparison of the subcellular distribution of the messages encoding PLP and DM-20
1Department of Biochemistry, University of Stirling, Scotland.
Biochemical Genetics
|February 1, 1997
Abstract:
Oligonucleotides provide a means to differentiate between closely related mRNAs. Here in situ hybridization is performed using oligonucleotide probes to determine the subcellular distribution of two differential splicing products of a single gene. It is demonstrated here that the subcellular distributions of PLP and DM-20 messages in oligodendrocytes are quite different, despite being transcripts of a single gene.