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Dynamic scintigraphy of bone and bone marrow in multiple myeloma patients with bone-marrow transplants
B Agren1, U Rudberg, P Aspelin
1Department of Diagnostic Radiology, Huddinge University Hospital, Sweden.
Purpose:
To determine whether dynamic registration at bone and bone-marrow scintigraphy produces additional information compared to subsequent static registrations of bone-marrow transplants in multiple myeloma patients.
Material And Methods:
In a prospective study, 8 dynamic bone and 6 dynamic bone-marrow scintigraphies were performed in 10 patients. The dynamic scintigraphies were compared with conventional radiography, MR images, and static scintigraphies of bone and bone marrow.
Results:
No additional information was revealed by the dynamic registration method; on the contrary, 4 of the 8 known lesions were not discerned at dynamic registration. An incidental observation was that the time-activity curves of both radiopharmaceuticals had a specific pattern.
Conclusion:
Dynamic registration at bone and bone-marrow scintigraphy was not useful for detecting disease in multiple myeloma lesions.