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Synthesis and antiparasitic activities of amidinic azolated derivatives
A Danan1, D Charon, S Kirkiacharian
1URA 1116 CNRS, Faculté de Pharmacie, Châtenay-Malabry, France.
Abstract:
A set of heterocyclic N-acetamidinium hydrochlorides were prepared from the corresponding N-acetonitriles. The antiparasitic screening showed that, while all amidines are practically inactive, some nitriles present leishmanicide properties.