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Medullary thyroid carcinoma: one component of the inherited disorder multiple endocrine neoplasia type 2A
1Seton Hall University Graduate School of Education, South Orange, NJ, USA.
Purpose/Objectives:
To describe and discuss the inherited syndrome multiple endocrine neoplasia (MEN) and one of its components medullary thyroid carcinoma.
Data Sources:
Published books and articles; clinical experience.
Data Synthesis:
Three distinct types of MEN are known. Type 2a consists of medullary thyroid carcinoma, pheochromocytoma, and other conditions. The disorder is autosomal-dominant. Genetic counseling and screening and biochemical screening are possible. Early detection and treatment are key to successful control.
Conclusions:
Identification of kindreds affected by this inherited disorder can result in improved detection and early treatment. The merit and value of presumptive treatment remain unclear. IMPLICATIONS FOR NURSING PRACTISE: Nursing activities encompass prediagnosis through postoperative phases. Care involves all members of the family as well as psychological care.