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A survey of pentobarbital sedation for children undergoing abdominal CT scans after oral contrast medium

P M Sanderson1

  • 1British Columbia Children's Hospital, Vancouver, Canada.

Paediatric Anaesthesia
|January 1, 1997
PubMed

Insights

Pediatric sedation for CT scans using oral contrast medium (OCM) with pentobarbital showed no failed sedations. However, complications like desaturation and airway issues occurred in 14.7% of cases.

Area of Science:

  • Pediatric Anesthesiology
  • Radiology
  • Pharmacology

Background:

  • Traditionally, radiologists manage pediatric sedation for imaging.
  • Increasing involvement of anesthesiologists in pediatric procedural sedation.
  • Oral contrast medium (OCM) in children undergoing CT scans presents unique sedation challenges.

Purpose of the Study:

  • To evaluate the safety and efficacy of intravenous pentobarbital for sedating children undergoing CT scans after OCM ingestion.
  • To identify common complications associated with this sedation protocol.

Main Methods:

  • Retrospective survey of 149 pediatric patients (3 months to 7 years) undergoing upper abdominal CT.
  • Intravenous pentobarbital was the primary sedative agent (average dose 4.6 mg/kg).
  • Supplementary sedation (midazolam +/- fentanyl) was used in a small subset of patients.

Main Results:

  • No failed sedations were recorded.
  • 141 patients (94.6%) received pentobarbital alone.
  • 36 complications occurred in 22 sedations (14.7%), including desaturation, vomiting, and airway obstruction.

Conclusions:

  • Intravenous pentobarbital is an effective sedative for pediatric CT scans with OCM, with a low failure rate.
  • Close monitoring is essential due to potential complications such as respiratory events and airway issues.

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