Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary carcinoid tumours: a comparative regional study

T Cooney, E C Sweeney, D Luke

    Journal of Clinical Pathology
    |November 1, 1979
    PubMed
    Summary

    Pulmonary carcinoid tumors show varied microscopic patterns, differing regionally. This study suggests local calcitonin may influence bronchial cartilage ossification in these rare lung cancers.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Imaging Butyrylcholinesterase in Multiple Sclerosis.

    Molecular imaging and biology·2020
    Same author

    Herpes simplex encephalitis and sarcoidosis.

    Irish journal of medical science·2016
    Same author

    Granulosa cell tumour of the ovary metastasising to the heart: A light and electron microscopic study.

    Irish journal of medical science·2016
    Same author

    Non-cirrhotic portal hypertension in Felty's syndrome.

    Irish journal of medical science·2016
    Same author

    Transbronchial brushing of peripheral lung lesions.

    Irish journal of medical science·2016
    Same author

    Calibration of the small bowel in stricture-forming small-bowel Crohn's disease.

    Annals of the Royal College of Surgeons of England·2014

    Area of Science:

    • Pulmonary pathology
    • Surgical pathology
    • Oncology

    Background:

    • Pulmonary carcinoid tumors are rare neuroendocrine neoplasms of the lung.
    • Previous studies, particularly from Japan, have reported specific histopathological patterns.
    • Understanding regional variations in tumor presentation is crucial for accurate diagnosis and treatment.

    Purpose of the Study:

    • To analyze the histopathological features of pulmonary carcinoid tumors in a specific cohort.
    • To compare these findings with existing literature, particularly Japanese studies.
    • To explore potential pathogenetic mechanisms, such as the role of calcitonin in cartilage ossification.

    Main Methods:

    • Retrospective review of 22 pulmonary carcinoid tumor cases over 11 years.
    • Microscopic examination focusing on tumor patterns and cell-nest formation.
    • Histopathological analysis including assessment of cartilage ossification.

    Main Results:

    • A total of 22 pulmonary carcinoid tumors (18 central, 4 peripheral) were identified.
    • The majority exhibited a mixed histopathological pattern.
    • Cell-nest formation was a prominent feature in 16 cases, differing from some reported series.

    Conclusions:

    • Findings suggest significant regional variations in the histopathological patterns of pulmonary carcinoid tumors.
    • A potential causal link between locally produced calcitonin and bronchial cartilage ossification within these tumors is hypothesized.
    • Further research is warranted to confirm these observations and elucidate the underlying mechanisms.

    Related Experiment Videos