Myxoglobulosis in an extravasation mucocele of the lower lip

A case of extravasation mucocele showing an unusual intraluminal globular organization of the mucous content is described. The cystic lesion was obtained from the lower lip of a 10-year-old Japanese girl and presented as a painless swelling of 1 year duration. Histologically, the cyst cavity was filled with round globules and encapsulated by a granulation tissue wall devoid of a lining epithelium. To our knowledge this peculiar histological pattern has not been previously described in an oral mucocele. Clinicopathological features of 'myxoglobulosis of the appendix', a morphological variant of appendiceal mucocele, appear to be related to the present case.