Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Renal involvement in multiple myeloma

B N Taparia1, B Bahel, B V Shah

  • 1Department of Nephrology; National Health and Education Society, Mahim, Bombay.

The Journal of the Association of Physicians of India
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Describing county-level clustering patterns of suicide among Veterans Health Administration patients and all American adults, 2018-2019, using exploratory spatial data analysis.

Annals of epidemiology·2025
Same author

Learning Curve for Flow Diversion of Posterior Circulation Aneurysms: A Long-Term International Multicenter Cohort Study.

AJNR. American journal of neuroradiology·2022
Same author

In and around the pineal gland: a neuroimaging review.

Clinical radiology·2021
Same author

A Deep Learning-Based Approach to Reduce Rescan and Recall Rates in Clinical MRI Examinations.

AJNR. American journal of neuroradiology·2019
Same author

Baseline Anti-blood Group Antibody Titers and their Response to Desensitization and Kidney Transplantation.

Indian journal of nephrology·2017
Same author

SU-E-T-108: 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique.

Medical physics·2017

This study found that nearly half of multiple myeloma patients developed renal failure, often linked to hypercalcemia. Treatment improved kidney function in most cases, with good long-term survival rates.

Area of Science:

  • Nephrology
  • Oncology
  • Internal Medicine

Background:

  • Multiple myeloma is a plasma cell malignancy.
  • Renal failure is a common complication in multiple myeloma patients.
  • Understanding risk factors and outcomes is crucial for patient management.

Purpose of the Study:

  • To analyze the incidence and precipitating factors of renal failure in multiple myeloma patients.
  • To evaluate the impact of treatment on renal function in this cohort.
  • To determine the survival rates for multiple myeloma patients with renal failure.

Main Methods:

  • Retrospective chart analysis of 33 multiple myeloma patients.
  • Identification of patients who developed renal failure.
  • Analysis of precipitating factors including dehydration, hypercalcemia, and NSAID use.

Related Experiment Videos

  • Assessment of renal function improvement and survival rates post-treatment.

    • Main Results:

    • Sixteen (49.5%) patients developed renal failure, with a mean age of 59.2 years.
    • Hypercalcemia was a significant risk factor (relative risk 5.4) for renal failure.
    • Renal function improved in 68.7% of patients with hydration, hypercalcemia treatment, and chemotherapy.
    • One and 3-year actuarial survival rates were 87% and 74%, respectively.

    Conclusions:

    • Renal failure is a frequent complication of multiple myeloma, strongly associated with hypercalcemia.
    • Multimodal treatment including hydration, hypercalcemia management, and chemotherapy can improve renal function.
    • Multiple myeloma patients with renal failure maintain favorable long-term survival with appropriate management.