Related Experiment Video
Updated: Aug 14, 2026

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions
Published on: August 12, 2010
Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris
R P Reed1, C M Cooke-Yarborough, A L Jaquiery
1Microbiology Department, Royal Melbourne Hospital, VIC. vgs@mis.medrmh.unimelb.edu.au
Abstract:
Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris is rare (63 human) cases reported worldwide) and fatal. We report a case in a five-year-old boy who had previously been well. For 18 months, he had had a slowly progressive, granulomatous mid facial lesion, but despite extensive investigation definitive diagnosis was made only with the acute onset of neurological signs in the last two weeks of life, when a brain biopsy specimen revealed amoebic trophozoites and cysts. Infection with B. mandrillaris should be considered in the differential diagnosis of chronic skin lesions with non-specific granulomatous histopathology and negative microbiological test results.
More Related Videos
Related Concept Videos
Bacterial Meningitis
Cryptococcal Meningitis
Amebiasis
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Encephalitis l: Introduction

