Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allergy and SLE: common and variable

E Shahar1, M Lorber

  • 1Institute of Clinical Immunology, Allergy and AIDS, Rambam Medical Center, Haifa, Israel.

Israel Journal of Medical Sciences
|February 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Continuum of HIV care of newly diagnosed individuals in Israel, 2011-2015: a population-based cohort study.

International journal of STD & AIDS·2020
Same author

Identification and characterization of HIV positive Ethiopian elite controllers in both Africa and Israel.

HIV medicine·2018
Same author

The effect of ongoing blood loss on human serum concentrations of perfluorinated acids.

Chemosphere·2014
Same author

The contribution of diet to total bisphenol A body burden in humans: results of a 48 hour fasting study.

Environment international·2012
Same author

Di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) metabolism in a human volunteer after single oral doses.

Archives of toxicology·2012
Same author

Letter to the editor, "influence of experimental acidification on sleep bruxism: a randomized trial".

Journal of dental research·2011
Same journal

Coronary revascularization versus conservative medical management for preoperative optimization of a patients with documented ischemic heart disease.

Israel journal of medical sciences·1998
Same journal

Primary biliary cirrhosis--association or overlap with other autoimmune diseases.

Israel journal of medical sciences·1998
Same journal

Complementary medicine--the problem and the challenge.

Israel journal of medical sciences·1998
Same journal

Electroencephalography in the evaluation of headache patients: a review.

Israel journal of medical sciences·1998
Same journal

Complementary medicine--a critical review.

Israel journal of medical sciences·1998
Same journal

The Israel Longitudinal Mortality Study--differential mortality in Israel 1983-1992: objectives, materials, methods and preliminary results.

Israel journal of medical sciences·1998
See all related articles

Patients with systemic lupus erythematosus (SLE) have a higher incidence of allergic disorders. Immune dysregulation in SLE may predispose individuals to conditions like IgE-mediated allergies.

Area of Science:

  • Immunology
  • Rheumatology
  • Allergology

Background:

  • Autoimmune conditions and allergic diseases share underlying immune dysregulation.
  • Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease with complex immune system alterations.

Purpose of the Study:

  • To determine the frequency of allergic disorders in patients diagnosed with SLE.
  • To investigate the potential link between SLE-related immune perturbations and the development of allergies.

Main Methods:

  • A case-control study involving 60 SLE patients and 60 age/sex-matched healthy controls.
  • Data collection via questionnaires detailing the presence of various allergic disorders.
  • Comparison of allergic disorder incidence between the SLE group and the control group.

Related Experiment Videos

Main Results:

  • A significant proportion of SLE patients (56%) reported at least one allergic disorder.
  • The incidence of allergic conditions was notably higher in the SLE cohort compared to healthy controls.
  • Specific types of allergic disorders were more prevalent in SLE patients, suggesting a connection.

Conclusions:

  • Immune dysregulation characteristic of SLE may enhance susceptibility to allergic diseases.
  • Findings suggest a potential role for altered immunoregulation in the pathogenesis of IgE-mediated allergic disorders in SLE patients.
  • Further research is warranted to elucidate the precise mechanisms linking SLE and allergic conditions.