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A new method for absolute quantitation of MRS metabolites
L Barantin1, A Le Pape, S Akoka
1INSERM U316, Laboratoire de Biophysique Cellulaire et RMN, Faculté de Médecine, Tours, France.
Magnetic Resonance in Medicine
|August 1, 1997
Abstract:
A new method for absolute quantitation of MRS spectra is presented. This method is not based on a reference peak, derived from a real NMR signal, but rather on a synthesized NMR reference produced by an electronic device, transmitted by a broad-band antenna to avoid quality factor variations. This signal is therefore received at the same time as the sample signal. The reference line produced is stable in time (maximum variation lower than 2%) and allows precise and accurate measurement of absolute concentrations (mean error lower than 3%) in vitro and in vivo.