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Related Experiment Videos

Thyrotoxic vomiting. A case report

M Arthurs1, R Green, C Sirju

  • 1Department of Medicine, University of the West Indies, Jamaica.

The West Indian Medical Journal
|June 1, 1997
PubMed
Summary
This summary is machine-generated.

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A postmenopausal woman experienced severe vomiting and weight loss due to elevated thyroid hormones. Treatment with antithyroid medication and propranolol resolved symptoms, leading to a good outcome after radioactive iodine therapy.

Area of Science:

  • Endocrinology
  • Internal Medicine
  • Thyroidology

Background:

  • Thyrotoxicosis can present with atypical symptoms, particularly in postmenopausal women.
  • Severe vomiting and weight loss may be the primary manifestations of hyperthyroidism.
  • Subtle or absent classic signs of thyrotoxicosis can complicate diagnosis.

Observation:

  • A postmenopausal female presented with severe vomiting and significant weight loss.
  • Laboratory tests revealed elevated thyroid hormone levels, suggestive of thyrotoxicosis.
  • Classic signs and symptoms of thyrotoxicosis were not apparent at the time of initial presentation.

Findings:

  • Antithyroid therapy using carbimazole and propranolol led to rapid symptom resolution.
  • The patient experienced marked improvement in her overall well-being following initial treatment.

Related Experiment Videos

  • Subsequent radioactive iodine ablation of the thyroid gland resulted in a long-term asymptomatic state.

    • Implications:

    • This case highlights the importance of considering thyrotoxicosis in postmenopausal women presenting with unexplained vomiting and weight loss, even without overt thyrotoxic symptoms.
    • Early and appropriate medical management, followed by definitive therapy, can effectively control severe thyrotoxicosis.
    • The successful treatment strategy underscores the efficacy of a multi-modal approach in managing complex thyroid disorders.