Related Experiment Video

Updated: Feb 8, 2026

Isolation and Culture of Resident Cardiac Macrophages from the Murine Sinoatrial and Atrioventricular Node
08:43

Isolation and Culture of Resident Cardiac Macrophages from the Murine Sinoatrial and Atrioventricular Node

Published on: May 7, 2021

5.2K

Symptomatic atrioventricular block in an atriofascicular pathway inserting into the left bundle branch without

A Mecca1, A Telfer, C Lanzarotti

  • 1Section of Electrophysiology, Loyola University Medical Center, Maywood, Illinois 60153, USA.

Journal of Cardiovascular Electrophysiology
|August 1, 1997
PubMed

Insights

This study details a unique case of symptomatic atrioventricular (AV) block caused by conduction only through an atriofascicular pathway. This pathway bypassed the AV node, leading to abnormal heart rhythms.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Human Physiology

Background:

  • Atrioventricular (AV) block is a condition where the electrical signal is slowed or blocked between the atria and ventricles.
  • Conduction abnormalities can arise from various pathways, impacting cardiac function.
  • Understanding accessory pathways is crucial for diagnosing and managing arrhythmias.

Observation:

  • A patient presented with symptomatic AV block.
  • Cardiac conduction was exclusively observed through an atriofascicular pathway.
  • This pathway connected to the left bundle branch, with no apparent AV node conduction.

Findings:

  • The patient's AV block was solely mediated by an atriofascicular pathway, bypassing the AV node.
  • Passive activation of the His-Purkinje system was noted.
  • His-bundle pacing confirmed normal conduction in both the right and left bundles, indicating the His-Purkinje system was intact.

Implications:

  • This case highlights a previously unreported mechanism of AV block involving an atriofascicular pathway.
  • It expands the understanding of cardiac conduction disorders and accessory pathways.
  • Further research may elucidate the prevalence and clinical significance of such pathways.

More Related Videos

Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse05:16

Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse

Published on: December 22, 2020

6.7K
Biaxial Mechanical Characterizations of Atrioventricular Heart Valves11:00

Biaxial Mechanical Characterizations of Atrioventricular Heart Valves

Published on: April 9, 2019

14.9K

Related Concept Videos

Apparent Weight01:09

Apparent Weight

True weight is the measure of the gravitational force acting on an object. However, if the object accelerates, its measured weight is different from its true weight. Similar observations can be made when the object is submerged in water. An object's weight in water is its apparent weight, which is equal to the difference between its true weight and the buoyant forces.
Consider a person standing on a bathroom scale inside an elevator. If the scale is accurate at rest, its reading equals the...
9.8K
Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
4.9K
C4 Pathway and CAM01:27

C4 Pathway and CAM

Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
49.2K
Apparent Weight and the Earth's Rotation01:28

Apparent Weight and the Earth's Rotation

Since all objects on the Earth's surface move through a circle every 24 hours, there must be a net centripetal force on each object, directed towards the center of that circle. The points of the north and south poles are the only exception to this rule.
For an object on the Earth's equator, the net centripetal force that accounts for its rotation is the Earth's pull towards its center, or the weight minus the normal force that prevents it from piercing into the Earth's surface....
4.1K
Block Diagram Reduction01:22

Block Diagram Reduction

The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
567
Elements of Block Diagrams01:25

Elements of Block Diagrams

Block diagrams serve as a visual representation of the input-output relationships within a system. An illustrative example is a heating system, where the set temperature activates the furnace to warm the room to the desired level. Block diagrams are versatile, modeling linear systems through Laplace transform variables and nonlinear systems using time domain variables.
A block diagram typically includes essential elements such as comparators, blocks, and feedback loops. Each of these elements...
715