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Plateletapheresis with a next generation blood cell separator
E A Burgstaler1, A A Pineda, B M Potter
1Division of Transfusion Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Journal of Clinical Apheresis
|January 1, 1997
Summary
The Amicus apheresis system significantly reduces platelet collection times and improves white blood cell (WBC) reduction compared to the CS 3000+. This advancement in apheresis technology enhances platelet collection efficiency and donor retention.
Area of Science:
- Hematology
- Transfusion Medicine
- Medical Device Technology
Background:
- Procedure time is critical for apheresis platelet donor retention.
- Next-generation apheresis systems aim to improve efficiency and product quality.
Purpose of the Study:
- To evaluate the Fenwal Amicus apheresis system.
- To compare Amicus performance against the Fenwal CS 3000+.
Main Methods:
- Clinical trial of the Amicus prototype (30 double-needle procedures).
- Comparison of Amicus (20 double-needle) vs. CS 3000+ (20 double-needle).
- Analysis of processing times, platelet yields, collection efficiency, and WBC content.
Main Results:
- Amicus processing time averaged 61 minutes, with 63% < 60 minutes.
- Amicus showed significantly shorter processing times (64 vs. 86 min) and higher collection rates than CS 3000+.
- Amicus provided superior WBC reduction compared to CS 3000+.
Conclusions:
- The Amicus system offers significantly shorter processing times and better WBC reduction than the CS 3000+.
- Amicus achieves comparable platelet yields with improved efficiency.
- Encouraging results were observed for Amicus single-needle procedures.