Mean corpuscular volume-dependent deviations in red blood cell distribution width between Sysmex NE-8000 and SF-3000

Values for red blood cell distribution width yield information concerning size heterogeneity of red blood cell populations. Comparative studies between various haematology analysers are obligatory to quantify apparatus-dependent deviations with respect to accuracy and subsequent consequences with respect to clinical interpretation of results. In this study a comparative assessment is performed between a Sysmex SF-3000 and NE-8000 Haematology Analyser. Fifty-four specimens with abnormal red blood cell volumes and a hundred specimens from apparently healthy subjects were assayed. Systematic deviations in values concerning red blood cell distribution width are demonstrated to show a tendency to decrease towards higher mean corpuscular volume values.