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Updated: Aug 19, 2026
The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
[An analysis of the prognostic factors in renal-cell carcinoma]
J Caballero Alcántara1, C Marchal Escalona, M Padilla León
1Unidad de Urología, Hospital Costa del Sol, Marbella, Málaga.
Objectives:
The study proposes the analysis of the influence of gross, microscopical and clinical pathoanatomical prognostic factors in the survival of patients with RCC through univariance and multivariance statistical analysis, and its global evaluation as a predictive model.
Patients And Method:
The study involved 218 RCC cases operated on over 20 years, with a mean follow-up of 60 months.
Results And Conclusions:
All prognostic factors studied have a significant influence on the survival. When studied jointly, they include separately and in order of significance the metastatic involvement, mitotic index, cava vein involvement, nuclear grade and sarcomatoid histologic pattern. Also, we confirm that considered jointly they conform a valid predictive model.
