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Seizures associated with cisplatin administration
A Brauers1, P Mattelaer, A Mersdorf
1Department of Urology, Medical Faculty, Technical University, Aachen, Germany.
European Urology
|January 1, 1997
Summary
Cisplatin chemotherapy for extragonadal germ cell tumors can cause rare seizures. This case highlights the neurotoxic effects of cisplatin, prompting a literature review on this adverse event.
Area of Science:
- Oncology
- Neuroscience
- Pharmacology
Background:
- Primary extragonadal germ cell tumors are rare malignancies.
- Cisplatin-based chemotherapy is a standard treatment for germ cell tumors.
- Neurotoxicity is a known, albeit uncommon, side effect of cisplatin.