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An overview on chemical modification of enzymes. The use of group-specific reagents
1Laboratorio de Bioquímica, Pontificia Universidad Católica de Chile, Santiago, Chile. jeyzag@genes.bio.puc.cl
Biological Research
|January 1, 1996
Abstract:
Chemical modification is an important approach to the study of enzyme active sites. This article presents an overview of the methods used. The basic concepts, applications and limitations of chemical modification are outlined. The use of reagents specific for different amino acid side chains is also discussed.