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A light-driven rhythm in neurotensin-like immunoreactivity in the chicken retina
1Centre for Visual Science and Research School of Biological Science, Australian National University, Canberra, Australia.
Purpose:
To determine if the pattern of release of neurotensin from the enkephalin-, neurotensin- and somatostatin-like immunoreactive amacrine cells in response to light and dark is the same as that of the enkephalins and somatostatin.
Methods/Results:
Both the enkephalins and somatostatin are released at high rates in the dark and at lower rates in the light, and these rate changes are reflected in increasing intracellular levels of the peptides in vivo in the light and decreasing levels in the dark. The levels of neurotensin-like immunoreactivity show a similar diurnal light-driven and non-circadian rhythm in vivo.
Conclusion:
This implies that the actual release rates of neurotensin follow the same patterns as those demonstrated in vitro for the enkephalins and somatostatin.