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Asthma: pathophysiology and clinical correlates

E R McFadden, N T Feldman

    The Medical Clinics of North America
    |November 1, 1977
    PubMed
    Summary
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    Clinical assessment of acute asthma can predict airway obstruction severity and treatment response. Objective measurements are crucial for severe cases when clinical predictions deviate, guiding therapy effectiveness.

    Area of Science:

    • Pulmonology
    • Critical Care Medicine

    Background:

    • Acute asthma requires accurate assessment of airway obstruction.
    • Clinical evaluation is the traditional method for determining severity and treatment response.

    Purpose of the Study:

    • To evaluate the utility of clinical assessment in acute asthma.
    • To determine when objective measurements are necessary for managing severe asthma.

    Main Methods:

    • Analysis of presenting signs and symptoms in acute asthma patients.
    • Comparison of clinical assessment with objective measurements in severe cases.

    Main Results:

    • Clinical analysis can reliably predict airway obstruction and response to therapy.
    • Objective measurements are vital when patients with severe obstruction do not follow expected clinical courses.

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    Conclusions:

    • Clinical assessment is valuable for initial acute asthma evaluation.
    • Objective measures of mechanical function and gas exchange are essential for guiding therapy in severe, atypical asthma cases.