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[Cholestatic hepatitis caused by amoxycillin-clavulanic acid. Report of a new case]
M Bustamante Balén1, F Pérez Aguilar, M Rayón Martín
1Servicio de Medicina Digestiva, Hospital Universitario La Fe, Valencia.
Gastroenterologia Y Hepatologia
|April 1, 1997
Abstract:
Toxic hepatitis is an infrequent secondary effect of amoxycillin-clavulanic acid with fewer than 30 well documented cases in the literature. Presentation is usually that of acute cholestasis several weeks after the initiation of treatment with this antibiotic. A new case of hepatic toxicity by amoxycillin-clavulanic acid is reported in a 47-years-old male who had taken this drug for a diarrhea syndrome. A brief review of the literature is made with special emphasis on the anatomopathologic aspects.