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Inflammatory pseudotumor of the choroid plexus

M Bramwit1, P Kalina, M Rustia-Villa

  • 1Department of Radiology, North Shore University Hospital, New York University School of Medicine, Manhasset 11030, USA.

Insights

A rare inflammatory pseudotumor mimicked a meningioma on imaging. Histology confirmed a non-neoplastic inflammatory lesion, successfully resected with no recurrence.

Area of Science:

  • Neuropathology
  • Neuroradiology
  • Neurosurgery

Background:

  • Inflammatory pseudotumors are rare, benign lesions that can occur in various locations.
  • Distinguishing inflammatory pseudotumors from neoplastic lesions can be challenging, especially in the brain.

Observation:

  • A case is presented of an intraventricular lesion with imaging characteristics suggestive of a meningioma.
  • CT demonstrated a hyperdense lesion with a trapped temporal horn.
  • MRI revealed decreased T1 and markedly hypointense T2 signals with homogeneous enhancement.

Findings:

  • Radiological and gross examination were consistent with meningioma.
  • Histological examination revealed the lesion was composed entirely of inflammatory, nonneoplastic cells.
  • Surgical resection was performed.

Implications:

  • This case highlights the importance of histological examination for definitive diagnosis, even when imaging suggests a neoplastic process.
  • Accurate diagnosis is crucial for appropriate management and to avoid unnecessary oncological treatment.
  • Complete resection of inflammatory pseudotumors can lead to favorable outcomes with no recurrence.

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