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Flat adenoma of the colon: two cases
P C Huang1, M J Shieh, J T Liang
1Department of Pathology, National Taiwan University Hospital, Taipei, ROC.
Journal of the Formosan Medical Association = Taiwan Yi Zhi
|August 1, 1997
Summary
Flat adenomas, sessile colonic lesions, show higher malignant potential. Early endoscopic detection and treatment are crucial for managing these lesions and preventing progression.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Oncology
Background:
- Flat adenomas are sessile, discolored mucosal lesions in the colon.
- These lesions possess a higher risk of malignant transformation compared to polypoid adenomas.
- The detection and management of flat adenomas have not been previously documented in Taiwan.
Observation:
- Two cases of flat adenoma were identified during colonoscopic examinations in Taiwan.
- Lesions presented as discolored, irregular mucosal patches.
- Histopathology confirmed adenomas with mild to moderate dysplasia.
Findings:
- Patient 1, with focal malignancy, underwent segmental colectomy and showed no recurrence.
- Patient 2, with tubular adenoma without malignancy, was treated with endoscopic strip biopsy but refused further surgery.
- Patient 2 later developed an enlarged sessile lesion.
Implications:
- Highlights the endoscopic and pathological features of flat adenoma.
- Emphasizes the critical need for early detection and prompt treatment of flat adenomas.
- Raises physician awareness regarding the potential malignancy of flat adenomas in Taiwan.