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Transient hyperammonaemia in an adult German shepherd dog
R G Lobetti1, D B Miller, T Dippenaar
1Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
Journal of the South African Veterinary Association
|June 1, 1997
Abstract:
A 3-year-old male German shepherd dog was presented with severe generalised seizures. The dog was protein-intolerant and showed severe hyperammonaemia on ammonia stimulation. The hyperammonaemic state was present for at least 6 weeks and then spontaneously resolved. No obvious cause (liver disease, portocaval shunts, urea cycle enzyme deficiencies, drug therapy or urinary tract obstruction) could be identified. It is possible that this dog had a variation of transient hyperammonaemic syndrome, described in man and recently in a juvenile Irish wolfhound, that extended into adulthood.