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Co-existence of hypertension and abnormal lipid profile: a hospital-based retrospective survey

S J Joglekar1, S L Warren, A T Prabhu

  • 1Medical and Research Division, Pfizer Ltd., Mumbai.

Indian Heart Journal
|May 1, 1997
PubMed

Insights

This study found high rates of abnormal lipid profiles and glucose metabolism in Indian hypertensive patients. These coronary risk factors were more common in men, highlighting a need for targeted interventions.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Limited Indian data exists on the co-occurrence of coronary risk factors.
  • Hypertension is a significant cardiovascular risk factor, often associated with metabolic abnormalities.

Purpose of the Study:

  • To determine the prevalence of abnormal lipid profiles and glucose metabolism among hypertensive individuals in India.
  • To assess the co-existence of these risk factors in a hypertensive population.

Main Methods:

  • Retrospective analysis of 500 consecutive health check-up records of hypertensive patients.
  • Screening for abnormal cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, and fasting blood sugar levels.

Main Results:

  • 57% had cholesterol ≥ 200 mg/dl; 47% had an elevated total to HDL cholesterol ratio (> 4.5).
  • 34% had triglycerides ≥ 200 mg/dl (5% had ≥ 400 mg/dl).
  • 20% had abnormal glucose metabolism (on antidiabetic drugs or fasting blood sugar > 120 mg/dl). Lipid abnormalities were more prevalent in males (p < 0.05).

Conclusions:

  • Hypertensive patients in India frequently exhibit abnormal lipid profiles and glucose metabolism.
  • These co-existing risk factors, particularly in males, necessitate comprehensive cardiovascular risk management strategies.

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