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Oesophageal involvement in cicatricial pemphigoid
L J Warren1, F Wojnarowska, J D Wilkinson
1Dermatology Department, Amersham Hospital, United Kingdom.
The Australasian Journal of Dermatology
|August 1, 1997
Summary
Cicatricial pemphigoid can affect the esophagus, causing dysphagia and requiring combined drug therapy and esophageal dilation for symptom management. Dermatologists must screen for swallowing issues in patients with this condition.
Area of Science:
- Dermatology
- Gastroenterology
- Immunopathology
Background:
- Cicatricial pemphigoid is an autoimmune blistering disease that can affect mucous membranes.
- Oesophageal involvement is a rare but serious complication.
Observation:
- Four cases of cicatricial pemphigoid with oesophageal involvement are presented.
- Patients experienced dysphagia, with radiological studies confirming oesophageal ulceration, webs, and strictures.
Findings:
- Diagnosis of oesophageal involvement often requires repeated radiological studies.
- Successful management involved a combination of systemic drug therapy and oesophageal dilatation.
Implications:
- Dermatologists should actively inquire about swallowing difficulties in cicatricial pemphigoid patients.
- Early recognition and intervention are crucial for managing oesophageal complications and improving patient outcomes.