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Testosterone-regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas
1Department of Pharmacology and Toxicology, Philipps University, Marburg, Germany.
Journal of Bacteriology
|September 19, 1997
Abstract:
The effect of testosterone as the sole carbon source on protein expression was analyzed in Comamonas testosteroni. Testosterone simultaneously induced the expression of steroid- and aromatic hydrocarbon-catabolizing enzymes and repressed one amino acid-degrading enzyme. It is suggested that steroids play a regulative role in catabolic enzyme synthesis during adaptive growth of C. testosteroni.