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Partial reversal of heparin anticoagulation by intravenous protamine in abciximab-treated patients undergoing

D J Kereiakes1, T M Broderick, D D Whang

  • 1Carl and Edyth Lindner Center for Clinical Cardiovascular Research, The Health Alliance of Greater Cincinnati, Ohio 45219, USA.

The American Journal of Cardiology
|September 19, 1997
PubMed

Serious hemorrhage and vascular complications after abciximab therapy are associated with elevated activated clotting time values. Our preliminary experience suggests that low-dose intravenous protamine administration is both safe and effective in reducing elevated in-laboratory activated clotting time values and the potential for serious hemorrhage in abciximab-treated patients.

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