[Surgical management of coarctation of the aorta in early infants]
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Published on: October 6, 2022
Insights
Prosthetic patch aortoplasty and end-to-end anastomosis are effective surgical options for infant coarctation of the aorta. These procedures show good long-term outcomes with minimal recoarctation, improving aortic arch dimensions.
Area of Science:
- Pediatric Cardiac Surgery
- Congenital Heart Disease
- Aortic Coarctation Repair
Context:
- Infants under three months with coarctation of the aorta require timely surgical intervention.
- Surgical repair methods have evolved, impacting early mortality and long-term outcomes.
- Coarctation of the aorta presents with varying complexity, including associated cardiac defects.
Purpose:
- To evaluate the efficacy and outcomes of prosthetic patch aortoplasty and end-to-end anastomosis for coarctation of the aorta in infants.
- To assess early mortality, long-term clinical course, and hemodynamic results after surgical repair.
- To compare pre- and postoperative aortic arch dimensions and identify residual pressure gradients.
Summary:
- Thirteen infants underwent aortic coarctation repair using prosthetic patch plasty (11) or end-to-end anastomosis (1).
- Early mortality was 23%, but improved with PGE1 therapy. Long-term follow-up showed good clinical courses, no significant residual gradients, and improved aortic arch indices.
- Prosthetic patch aortoplasty and end-to-end anastomosis are deemed adequate surgical options for early infant coarctation of the aorta.
Impact:
- Surgical techniques like prosthetic patch aortoplasty offer favorable outcomes for infant coarctation.
- Improved aortic arch dimensions post-surgery suggest successful relief of obstruction.
- The study supports the use of these methods for managing severe coarctation in neonates and young infants.
Abstract:
Thirteen infants under three months old were repaired aortic coarctation between 1980 and 1988. The mean age at operation was 2 +/- 0.8 months, the mean weight was 3.7 +/- 0.6 kg. Patients were simple coarctation in 1, coarctation with VSD in 7, and coarctation with complex heart disease in 5. As the operative method, the prosthetic patch plasty was done in 11 patients, end to end anastomosis in 1 patient and remaining one was primary VSD closure and secondary coarctation repair (patch plasty). Three patients died perioperatively, the overall early mortality rate was 23%. Since the introduction of PGE1 therapy in 1985, operative mortality rate of the operation (patch aortoplasty) was improved dramatically. Two of 10 patients died from LOS after the secondary operation (one was TGA and another was congenital MS with VSD). Eight patients are alive and clinical course after operation had been good. The measurement of arm-leg pressure difference didn't reveal significant residual gradient. Postoperative isthmus index was 90 +/- 13% in follow up measurement. Recoarctation has not been occurred in patients undergoing operations with patch plasty. Postoperative hypoplastic arch index was 93 +/- 19% in 1 to 2 years after operation compared with 70 +/- 16% of the preoperation. Therefore, it is concluded that prosthetic patch aortoplasty and end to end anastomosis of the aorta are both available as reasonable and/or adequate operation for the early infants with coarctation.
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