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[Microcrystals and biliary sludge: pathogenesis and clinical significance]
J M Chebli1, E V Martins Júnior, A K Gaburri
1Universidade Federal de São Paulo-Escola Paulista de Medicina UNIFESP-EPM.
Abstract:
Review of the literature concerning the pathogenesis and the clinical significance of microcrystals and biliary sludge. In addition, the advantages and limitations of the available methodology of identification of these microscopic precipitates and the clinical conditions in which the investigation of the bile composition, with respect to the presence of cholesterol and calcium bilirubinate microcrystals, are discussed. In conclusion, algorithms for treatment of bileopancreatic diseases caused by microcrystals and/or biliary sludge are proposed.
Insights
This review covers microcrystals and biliary sludge, discussing their formation, clinical importance, and identification methods. Treatment algorithms for related bile-pancreatic diseases are proposed.
Area of Science:
- Gastroenterology and Hepatology
- Biliary System Pathophysiology