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Updated: Aug 14, 2026

Intracranial Injection of Adeno-associated Viral Vectors
Published on: November 18, 2010
Reporting vaccine-associated adverse events
1Division of Immunization, Bureau of Infectious Diseases, Health Canada's Laboratory Centre for Disease Control (LCDC), Ottawa.
Objective:
To determine family physicians' awareness of the need to monitor and report vaccine-associated adverse events (VAAE) in Canada and to identify mechanisms that could facilitate reporting.
Design:
Mailed survey.
Setting:
Canadian family practices.
Participants:
Random sample of 747 family physicians. Overall response rate was 32% (226 of 717 eligible physicians).
Main Outcome Measures:
Access to education on VAAE; knowledge about VAAE monitoring systems, reporting criteria, and reporting forms; method of reporting VAAEs and reasons for not reporting them; and current experience with VAAEs.
Results:
Of 226 respondents, 55% reported observing VAAEs, and 42% reported the event. Fewer than 50% were aware of a monitoring system for VAAE, and only 39% had had VAAE-related education during medical training. Only 28% knew the reporting criteria. Reporting was significantly associated with knowledge of VAAE monitoring systems and reporting criteria (P < 0.01).
Conclusion:
Physicians need more feedback and education on VAAE reporting and more information about the importance of reporting and about reporting criteria and methods.
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