Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hemodynamic and respiratory changes during lung transplant]

A Planas1, J I Lora-Tamayo, J I Gómez-Arnau

  • 1Servicio de Anestesiología y Reanimación, Clínica Puerta de Hierro, Madrid.

Revista Espanola De Anestesiologia Y Reanimacion
|June 1, 1997
PubMed
Summary

Sequential bilateral lung transplantation (SBLT) can cause significant hemodynamic instability and right ventricular (RV) dysfunction during reperfusion and ventilation of the first transplanted lung. Careful RV function monitoring is crucial for patient management during SBLT.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral Medicine in Latin America and the Caribbean: A comprehensive survey of recognition, training, and practice.

Medicina oral, patologia oral y cirugia bucal·2025
Same author

Ectopic expression of the cation-chloride cotransporter KCC2 in blood exosomes as a biomarker for functional rehabilitation.

Frontiers in molecular neuroscience·2025
Same author

[Extended length of stay following robot-assisted minimally invasive pulmonary lobectomy: Is incomplete ERAS protocol to blame?]

Revue des maladies respiratoires·2024
Same author

Preoperative coagulation screening tests in pediatric patients: Clinical relevance and hemorrhagic outcomes of abnormal results.

Revista espanola de anestesiologia y reanimacion·2023
Same author

Development, equivalence study, and normative data of version B of the Spanish-language Free and Cued Selective Reminding Test.

Neurologia·2021
Same author

[Psychometric properties of the Post-COVID 19 Functional Status scale for adult COVID 19 survivors].

Rehabilitacion·2021

Area of Science:

  • Cardiovascular Physiology
  • Thoracic Surgery
  • Transplantation Medicine

Background:

  • Lung transplantation is a complex procedure with potential for significant physiological changes.
  • Understanding hemodynamic and gasometric alterations is key to optimizing patient outcomes.
  • Comparing unilateral lung transplantation (ULT) with sequential bilateral lung transplantation (SBLT) provides insights into surgical-specific challenges.

Purpose of the Study:

  • To investigate the hemodynamic and gasometric changes during lung transplantation.
  • To compare these changes between unilateral (ULT) and sequential bilateral lung transplantation (SBLT).
  • To identify critical phases of instability during SBLT.

Main Methods:

  • Prospective study of 13 lung transplant recipients (8 ULT, 5 SBLT).

Related Experiment Videos

  • Continuous monitoring of hemodynamic and gasometric parameters, including right ventricular (RV) ejection fraction.
  • Statistical analysis using ANOVA and Neumann Keuls tests.

    • Main Results:

    • ULT showed minimal hemodynamic and gasometric changes.
    • SBLT demonstrated transient hemodynamic instability, including increased pulmonary artery pressure and decreased cardiac index.
    • Significant RV dysfunction and hypoxemia occurred during reperfusion/ventilation of the first transplanted lung in SBLT.

    Conclusions:

    • The reperfusion and ventilation of the initial transplanted lung during SBLT represent a period of significant hemodynamic and ventilatory compromise.
    • Close monitoring of RV function is essential for managing patients undergoing SBLT.
    • Proactive management strategies are needed to address the instability observed during SBLT.