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Prostate cancer metastatic only to the penis
M M Celebi1, D D Venable, C Nopajaroonsri
1Section of Urology, Overton Brooks Veteran Affairs Medical Center, Shreveport, LA, USA.
Southern Medical Journal
|September 26, 1997
Summary
Metastatic prostate cancer to the penis is rare. This case study shows successful treatment of penile metastasis with radiation and androgen deprivation therapy, resolving pain and prolonging survival.
Area of Science:
- Urology
- Oncology
Background:
- Prostate cancer is a common malignancy in men.
- Metastasis of prostate cancer to the penis is an exceptionally rare event.
- Adjuvant radiotherapy is a standard treatment following radical prostatectomy for prostate cancer.
Observation:
- A patient presented with a painful nodule in the corpora cavernosa during adjuvant radiotherapy.
- The nodule was biopsied and revealed poorly differentiated adenocarcinoma.
- Immunohistochemical staining confirmed the prostatic origin of the neoplasm.
Findings:
- The penile lesion was treated with radiation therapy combined with androgen deprivation therapy.
- The patient experienced complete resolution of penile pain.
- The patient remained alive 30 months after the initiation of treatment.
Implications:
- This case highlights the possibility of penile metastasis from prostate cancer.
- Combined radiation and androgen deprivation therapy can be effective in managing this rare condition.
- Successful management can lead to symptom resolution and improved survival for patients with metastatic prostate cancer.