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Related Experiment Videos

The hepatitis C virus: overview

R Purcell1

  • 1Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0740, USA.

Hepatology (Baltimore, Md.)
|September 26, 1997
PubMed
Summary
This summary is machine-generated.

Hepatitis C virus (HCV) infection chronicity exceeds 80%. Understanding HCV's genetic diversity and immune response is crucial for developing a broadly protective vaccine against this flavivirus.

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Area of Science:

  • Virology
  • Immunology
  • Molecular Biology

Background:

  • Hepatitis C virus (HCV) was recognized in 1975 as non-A, non-B hepatitis.
  • HCV's genome was cloned and sequenced in 1989, leading to diagnostic assays.
  • HCV belongs to the Flaviviridae family, is an enveloped virus (approx. 50 nm), and possesses a positive-sense single-stranded RNA genome.