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Thyroid function in attention deficit and hyperactivity disorder

P Toren1, A Karasik, S Eldar

  • 1Tel Aviv Community Mental Health Center, Tel Aviv University, Israel.

Journal of Psychiatric Research
|May 1, 1997
PubMed
Summary
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This study found no significant association between thyroid function and attention deficit hyperactivity disorder (ADHD). Routine thyroid screening is not recommended for children diagnosed with ADHD.

Area of Science:

  • Endocrinology
  • Neurodevelopmental Disorders
  • Pediatrics

Background:

  • Conflicting findings exist regarding thyroid abnormalities and attention deficit hyperactivity disorder (ADHD).
  • Previous research has suggested a potential link, prompting further investigation.

Purpose of the Study:

  • To clarify the relationship between thyroid function and ADHD through a replication study.
  • To provide evidence-based recommendations for clinical guidelines regarding thyroid screening in ADHD.

Main Methods:

  • Thyroid function tests were conducted on 43 children with ADHD and 28 age- and gender-matched controls.
  • Assessed levels included total triiodothyronine (TT3), total thyroxine, free thyroxine, thyroid stimulating hormone, and TT3 reuptake.

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Main Results:

  • While 16 ADHD children had slightly elevated TT3 levels, no statistically significant difference was observed compared to controls.
  • No ADHD subjects exhibited abnormal levels of other tested thyroid hormones.

Conclusions:

  • The study provides further evidence against a causal link between thyroid dysfunction and ADHD.
  • Routine thyroid function screening in children with ADHD is not supported by these findings.