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Published on: November 29, 2018
[Prevalence of left ventricular hypertrophy in Danish patients with hypertension]
J Tingleff1, M Munch, T J Jakobsen
1Medicinsk afdeling C, Amtssygehuset i Glostrup, Befolkningsundersøgelsen i Glostrup.
Insights
Left ventricular hypertrophy (LVH) is more prevalent in hypertensive individuals, particularly older adults. This finding highlights the importance of blood pressure control in preventing cardiac changes.
Area of Science:
- Cardiology
- Hypertension Research
- Diagnostic Imaging
Context:
- Left ventricular hypertrophy (LVH) is a significant cardiac adaptation.
- Hypertension is a major risk factor for cardiovascular diseases.
- Understanding LVH prevalence in hypertensive populations is crucial for risk stratification.
Purpose:
- To investigate the prevalence of LVH in a hypertensive cohort compared to normotensive controls.
- To examine the relationship between hypertension and LVH across different age and sex groups.
Summary:
- A study involving 552 participants (358 hypertensive, 194 normotensive) assessed LVH using echocardiography.
- Overall LVH prevalence was 25%/26% (men/women) in hypertensives versus 14%/20% in normotensives.
- The association was significant in the 65-year-old group, indicating age-related differences.
Impact:
- LVH is significantly more common in hypertensive individuals, especially the elderly.
- The link between blood pressure and LVH is weak in the general population but pronounced in older hypertensives.
- Findings emphasize targeted screening for LVH in older hypertensive patients.
Abstract:
The aim of this investigation was to study the prevalence of left ventricular hypertrophy (LVH) in a hypertensive population with reference to a normotensive control group. From the general population, 3498 men and women aged 35, 45, 55 and 65 years old were invited to a health examination. Participants with blood pressure above 160 mmHg systolic and/or 95 mmHg diastolic or participants currently taking antihypertensive medication or having done so during the previous six months were asked to undergo an echocardiographic examination. Controls were randomly selected from the same population. Of 552 participants in the final study population, 194 were normotensive controls and 358 were in the hypertensive group. Echocardiographic measurements were made according to the "Penn" conventions and indexed for body surface. Cutoff values for LVH were 134 grams per m2 for males and 102 grams per m2 for women. Overall, we found that the prevalence of 1 VH was 14%/20% (men/women) in normotensives and 25%/26% in hypertensives (p < 0.01). By subdivision in age and sex groups we found that the relation between normotensives and hypertensives was significant in the age group of 65 years (p < 0.02 for males and p < 0.05 for females). The association between blood pressure and 1 VH in the general population is weak. 1 VH is only significantly more frequent among hypertensives as compared to normotensives in older people.
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