[Chemiluminescent study of free radical lipid peroxidation in the rabbit brain after cranio-cerebral trauma]

The method of chemiluminescence was applied for the determination of free radicals content in rabbit brain after the experimental craniocerebral trauma. The level of malondialdehyde was measured spectrophotometrically. The quantity of free radical products in hemispheres, brain stem and cerebellum of rabbits with traumatic injury was shown to be significantly increased and correlated with MDA level. Data obtained indicate that the chemiluminescent technique can be useful for the investigation of lipid peroxidation in brain pathology.