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Alternative splice variants of cytokines: making a list
1Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore 21201, U.S.A.
Life Sciences
|January 1, 1997
Abstract:
The cytokine network is an extremely complicated and redundant system of mutually interdependent pleiotropic cytokines that interacts with a variety of cells, tissues and organs producing various regulatory effects, both local and systemic. Recent studies have revealed a new source of complexity in the cytokine network--alternative splicing. This minireview attempts to summarize the available data on the alternative splicing of cytokines and its regulatory significance.