Related Experiment Video
Updated: Aug 12, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
Published on: November 15, 2013
[Receptor regulatory mechanisms of antimutagenic action]
1State Medical University, Kazan'.
Abstract:
Based on the data available in the literature and his own findings, the author suggests that there is a receptor regulatory mechanism of action in some antimutagens. The primary signal can be induced by an antimutagen at different stages of a regulatory cascade: a membrane, cell effectors, and cell ensembles. At the terminal stage, there is an activation of the natural system of antimutagenesis activates and an enhanced cell resistance to a mutagen.
Insights
Some antimutagens utilize a receptor regulatory mechanism to enhance cell resistance against mutagens. This involves signaling cascades that activate the natural antimutagenesis system.
Area of Science:
- Biochemistry
- Molecular Biology
- Genetics
Related Concept Videos
Mismatch Repair
Nucleotide Excision Repair
Nucleotide Excision Repair
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
Mismatch Repair
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
Mutagenicity and Carcinogenicity
Spontaneous and Induced Mutations

