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[Effect of the nerve growth factor on blood coagulation and fibrinolysis]
Eksperimental'Naia I Klinicheskaia Farmakologiia
|May 1, 1997
Abstract:
It was established in rabbit experiments that intravenous infusion of 150 BU/kg of the mouse nerve growth factor causes long-term hypocoagulation and simultaneous stimulation of fibrinolysis and anticoagulant activity. The essential role of the nerve growth factor in inducing the release of heparin and histamine into the blood and its contribution to the activation of other components of fibrinolysis and the antithrombine system is shown. This may be very important for the prevention of prethrombotic conditions in the future.