Related Experiment Videos
The importance of cellular environment to function of the CD44 matrix receptor
P W Kincade1, Z Zheng, S Katoh
1Oklahoma Medical Research Foundation, Oklahoma City 73104, USA. paul-kincade@omrf.ouhsc.edu
Current Opinion in Cell Biology
|October 23, 1997
Abstract:
Much has been learned recently by experimental manipulation of the structure of CD44 and assessment of the resulting functions. However, even greater structural variation is naturally introduced by CD44-bearing cells. A structural model is now available for the portion of CD44 that recognizes hyaluronan, but it is clear that all domains of the molecule influence CD44 functions.