Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Encapsulated filtering blebs after trabeculectomy with mitomycin-C

A Azuara-Blanco1, J B Bond, R P Wilson

  • 1Glaucoma Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.

Ophthalmic Surgery and Lasers
|October 23, 1997
PubMed
Summary

Guarded filtration with mitomycin-C has a low rate of encapsulated bleb formation. This complication occurred in only 2.47% of eyes, indicating a favorable safety profile for the procedure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Boat noise alters behaviour of two coral reef macroinvertebrates, Lambis lambis and Tridacna maxima.

Marine pollution bulletin·2025
Same author

A novel approach to seabird posture estimation: finding roll and yaw angles of dynamic soaring albatrosses using tri-axial magnetometers.

Royal Society open science·2023
Same author

Effect of bimatoprost sustained-release intracameral implant on intraocular pressure and medication burden in patients with prior glaucoma surgery.

Journal francais d'ophtalmologie·2023
Same author

Dead-reckoning elucidates fine-scale habitat use by European badgers <i>Meles meles</i>.

Animal biotelemetry·2023
Same author

Opioid analgesia in necrotizing pancreatitis: Incidence and timing of a hidden crisis.

American journal of surgery·2023
Same author

Cochrane Corner: evidence on the management of primary angle closure glaucoma.

Eye (London, England)·2022

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Surgical Complications

Background:

  • Glaucoma is a leading cause of irreversible blindness worldwide.
  • Filtration surgery is a common treatment for glaucoma, aiming to reduce intraocular pressure.
  • Mitomycin-C is an antifibrotic agent used to enhance filtration surgery outcomes but can be associated with complications.

Purpose of the Study:

  • To quantify the incidence of encapsulated blebs following guarded filtration surgery.
  • To evaluate the frequency of this specific complication when mitomycin-C is used adjunctively.

Main Methods:

  • Retrospective chart review of patients undergoing guarded filtration with mitomycin-C.
  • Inclusion criteria: minimum of 1 month follow-up.
  • Analysis of 283 cases from 235 patients.

Related Experiment Videos

Main Results:

  • Encapsulated blebs were identified in 7 eyes (2.47%) of 6 patients.
  • Diagnosis occurred at a mean of 29.7 days post-surgery.
  • Affected eyes had a mean intraocular pressure of 24.2 mmHg; 3 eyes received medical treatment, and 4 underwent needling.

Conclusions:

  • Guarded filtration procedures utilizing mitomycin-C demonstrate a low frequency of encapsulated bleb formation.
  • The findings suggest that this surgical approach is associated with a favorable safety profile regarding bleb encapsulation.