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Related Experiment Videos

Fornix-based trabeculectomy with mitomycin-C

H Levkovitch-verbin1, M Goldenfeld, S Melamed

  • 1Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel.

Ophthalmic Surgery and Lasers
|October 23, 1997
PubMed
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Fornix-based trabeculectomy with Mitomycin-C (MMC) is a safe and effective glaucoma treatment. This procedure significantly reduces intraocular pressure (IOP) with good long-term outcomes.

Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Glaucoma Management

Background:

  • Mitomycin-C (MMC) enhances trabeculectomy success, typically with limbal-based approaches.
  • Limited data exists on MMC's efficacy with fornix-based trabeculectomy.

Purpose of the Study:

  • To evaluate the safety and effectiveness of fornix-based trabeculectomy using Mitomycin-C (MMC).
  • To compare fornix-based trabeculectomy with MMC to traditional limbal-based methods.

Main Methods:

  • 71 glaucoma patients underwent fornix-based trabeculectomy with topical MMC (0.4 mg/ml for 3 minutes).
  • Conjunctiva-Tenon's capsule flap was secured to ensure watertight closure.
  • Mean follow-up duration was 14.5 months.

Main Results:

Related Experiment Videos

  • Preoperative mean intraocular pressure (IOP) was 32.4 mmHg; postoperative mean IOP decreased to 14.04 mmHg.
  • 80% of patients achieved an IOP of 20 mmHg or less.
  • 52% required no additional medical therapy post-surgery; complications like wound leakage and hypotony were minimal.

Conclusions:

  • Fornix-based trabeculectomy with intraoperative MMC application is a safe and effective glaucoma surgery.
  • This technique demonstrates comparable safety and efficacy to limbal-based trabeculectomy with MMC.