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Published on: November 3, 2009
[Long-term observations of ocular toxocariasis in children and youth]
K Krukar-Baster1, H Zygulska-Mach, K Sajak-Hydzik
1Katedry I Kliniki Okulistyki Collegium Medicum UJ w Krakowie.
Purpose:
To evaluate the clinical status and ELISA test changes in a group of children with ocular toxocariasis.
Methods:
We enrolled 37 patients in the studies. The follow-up period lasted at least 3 years (3-15 years) after the diagnosis had been established. In all cases a complete ophthalmological examination and actual ELISA test were performed. We compared the clinical status in two groups of patients: one with positive and the other with negative ELISA test at the time of control examination.
Results:
In a majority of initially positive serological patients the control ELISA test for Toxocara canis antigen was negative. In these cases various post-inflammatory lesions in the anterior and posterior pole of the eye were present. In 8 cases the ELISA test was positive, despite the absence of active inflammatory process. In 5 serologically positive patients the active inflammation was observed. In more than 50% of cases the visual acuity was decreased.
Conclusion:
Ocular toxocariasis is a long-lasting, severe type of uveitis that requires long treatment and causes dramatic visual impairment. ELISA test is a sensitive method indicating the intensity of inflammation in ocular toxocariasis.
