Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cardiovascular regulation in multiple sclerosis

B J Diamond1, H Kim, J DeLuca

  • 1Kessler Institute for Rehabilitation, Department of Research, West Orange, New Jersey 07052, USA.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional magnetic resonance imaging of working memory impairment after traumatic brain injury.

Journal of neurology, neurosurgery, and psychiatry·2001
Same author

A comparison of memory performance in relapsing-remitting, primary progressive and secondary progressive, multiple sclerosis.

Neuropsychiatry, neuropsychology, and behavioral neurology·2001
Same author

Ginkgo biloba extract: mechanisms and clinical indications.

Archives of physical medicine and rehabilitation·2000
Same author

Speed of information processing in traumatic brain injury: modality-specific factors.

The Journal of head trauma rehabilitation·2000
Same author

Speed of information processing as a key deficit in multiple sclerosis: implications for rehabilitation.

Journal of neurology, neurosurgery, and psychiatry·1999
Same author

Acquisition and storage deficits in multiple sclerosis.

Journal of clinical and experimental neuropsychology·1998
Same journal

UK consensus on pregnancy in multiple sclerosis: An update to 'Association of British Neurologists' guidance.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Comparative effectiveness of rituximab versus ocrelizumab in relapsing multiple sclerosis on clinical relapses and radiological outcomes in British Columbia, Canada.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Invisible symptoms in multiple sclerosis and their impact on social role participation: A multidimensional analysis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Interaction between smoking and <i>HLA-A*02:01</i> in multiple sclerosis progression.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Impact of multiple sclerosis disease-modifying therapies on chronic lesion tissue expansion.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same journal

Tobacco smoking disrupts bile acid and tryptophan metabolism in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
See all related articles

Multiple sclerosis patients have reduced vagal power, a measure of heart rate variability, indicating impaired autonomic nervous system control. This finding suggests heart rate variability may aid in diagnosing and managing MS-related cardiac issues.

Area of Science:

  • Cardiovascular Physiology
  • Neurology
  • Autonomic Nervous System Research

Background:

  • Traditional autonomic nervous system assessments are invasive.
  • Vagal power, a component of heart rate variability (HRV), offers a non-invasive method.
  • HRV reflects autonomic control of the heart.

Purpose of the Study:

  • To compare vagal power between multiple sclerosis (MS) patients and healthy controls.
  • To investigate the utility of HRV in assessing autonomic dysfunction in MS.
  • To explore potential diagnostic and prognostic applications of HRV in MS.

Main Methods:

  • Recruited 18 MS patients and 20 healthy subjects.
  • Matched subjects by age, education, and intelligence.
  • Measured vagal power during natural and paced breathing.

Related Experiment Videos

Main Results:

  • MS group exhibited significantly lower vagal power than healthy controls.
  • No significant difference in heart rate between the groups.
  • Vagal power was reduced during both natural and paced breathing in MS patients.

Conclusions:

  • MS patients demonstrate impaired cardiac parasympathetic control.
  • HRV, specifically vagal power, may serve as a diagnostic and prognostic tool in MS.
  • Further evaluation is needed on the impact of autonomic dysfunction on quality of life and cardiac events in MS.