Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visualizing cortical activation during mental calculation with functional MRI

L Rueckert1, N Lange, A Partiot

  • 1Cognitive Neuroscience Section, MNB, NINDS, National Institutes of Health, Bethesda, Maryland 20892-1440, USA.

Neuroimage
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the brain basis of self-monitoring.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

Noninvasive Assessment of Neurodevelopmental Disorders after In Utero Irradiation in Mice: An In Vivo Anatomical and Diffusion MRI Study.

Radiation research·2021
Same author

Clinical and MRI Predictors of Conversion From Mild Behavioural Impairment to Dementia.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry·2020
Same author

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2020
Same author

Active lifestyles moderate clinical outcomes in autosomal dominant frontotemporal degeneration.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2020
Same author

Aligning nomenclature for cognitive changes associated with anaesthesia and surgery with broader diagnostic classifications of non-surgical populations: a needed first step.

British journal of anaesthesia·2018
Same journal

Lifespan Trajectories of the Brain's Functional Complexity Characterized by Multiscale Sample Entropy.

NeuroImage·2026
Same journal

Pleasant fragrance modulates dyadic social sharing of positive emotion: Sharer-centered socioemotional enhancement effect and its neural couplings.

NeuroImage·2026
Same journal

Altered Functional Hierarchical and Sequential Organization in Individuals with Schizophrenia during Auditory Processing.

NeuroImage·2026
Same journal

Mechanical Deformation Explains Distinct Neuroimaging Patterns and Etiologies in Brain Trauma.

NeuroImage·2026
Same journal

Ventral striatum temporal interference brain stimulation enhances the reward-positivity event-related potential and reduces anxiety.

NeuroImage·2026
Same journal

NeuroHarm‑Kit: An Open‑Source Toolbox for Benchmarking Deep‑Learning Harmonization of Multi‑Site T1‑Weighted MRI.

NeuroImage·2026
See all related articles

This study used functional magnetic resonance imaging to observe brain activity during arithmetic calculations. Findings confirm the posterior parietal cortex is crucial for math, alongside premotor and prefrontal cortex areas.

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Neuroimaging

Background:

  • Understanding the neural basis of arithmetic calculation is essential for cognitive neuroscience.
  • Previous research suggests involvement of various brain regions, but precise localization and roles require further investigation.

Purpose of the Study:

  • To investigate cortical activation patterns during silent arithmetic calculation (subtraction by sevens) compared to a control task (counting by ones).
  • To identify specific brain regions, including the posterior parietal cortex, involved in mathematical processing.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) at 1.5-T was employed.
  • Nine healthy subjects performed silent subtraction by sevens and a forward counting task.
  • Cortical activation was analyzed and compared between the two conditions.

Related Experiment Videos

Main Results:

  • Bilateral activation was consistently observed in the premotor cortex, posterior parietal cortex, and prefrontal cortex during arithmetic calculation.
  • Significant individual variations in activation patterns were noted in regions beyond these core areas.
  • The posterior parietal cortex demonstrated significant activation, supporting its role in arithmetic.

Conclusions:

  • The study confirms the critical role of the posterior parietal cortex in arithmetic calculation.
  • It implicates the premotor and prefrontal cortex in mathematical processing.
  • Individual variability in neural activation highlights the complexity of arithmetic cognition.