Related Experiment Video
Updated: Aug 18, 2026
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Anaplastic large cell lymphoma mimicking noduloulcerative tertiary syphilis
T N Fotopoulos1, P D Shenefelt, J Messina
1Division of Dermatology and Cutaneous Surgery, College of Medicine, University of South Florida, Tampa 33612, USA.
Abstract:
Anaplastic large cell lymphoma (ALCL) is a recently described malignancy that can show heterogeneity in its clinical presentation. We report on a patient whose clinical presentation, medical history, and serologic test results were suggestive of tertiary syphilis. Histologic evaluation, however, revealed a large cell lymphoma with Ki-1 positive findings on immunostaining. We review the differential diagnosis of ALCL and add to that a pattern of ALCL clinically mimicking noduloulcerative tertiary syphilis.
