Related Experiment Video
Updated: Aug 16, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
False low pulse oximetry reading associated with the concomitant use of a peripheral nerve stimulator and an
I Keidan1, A Sidi, D Gravenstein
1Department of Anesthesiology, University of Florida College of Medicine, Gainesville 32610-0254, USA.
Abstract:
One of the sources of error in pulse oximetry readings is associated with an abnormal signal-to-noise ratio. The pulse oximeter distinguishes the light absorbance of arterial blood from that of other absorbers by differentiating between a constant component and a pulsating component. The pulsating component is almost exclusively the result of arteriolar bed pulsations. Because pulse oximetry is based on the assumption that arterial blood is the only pulsatile absorber, any other fluctuating phenomenon could constitute a source of error. We report a case in which a low pulse oximetry reading was associated with concomitant use of a pulse oximeter and a peripheral nerve stimulator on the same arm. Further tests conducted using a nerve stimulator and a sensory evoked potential stimulator with different amplitudes and frequencies confirmed the association and delineated the relationship between frequency and amplitude of stimulation and the degree of artificial desaturation. A theoretical explanation for this phenomenon is presented.
Related Concept Videos
Guidelines For Measuring Vital Signs
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.
Decreased pulse rate
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with bradycardia...
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is important.
Pulse
The pulse serves as a clinical indicator...
Pulse Oximetry
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...

