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Updated: Jul 21, 2026

Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II
Published on: February 26, 2018
Chiasmata, crossovers, and meiotic chromosome segregation
C A Bascom-Slack1, L O Ross, D S Dawson
1Department of Microbiology and Molecular Biology, Tufts University, Boston, Massachusetts 02111, USA.
Abstract:
Meiotic recombination events are probably critical for the completion of several meiotic processes. In addition, recombination is likely to be involved in the events that lead up to synapsis of homologues in meiotic prophase. Recombination events that ultimately become resolved as exchanges are needed for the formation of chiasmata. Chiasmata maintain the association of paired homologues following loss of the synaptonemal complex and participate in the mechanism that signals that the bivalent has attached to the spindle in a bipolar orientation that will result in meiosis I disjunction.
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