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Updated: Aug 17, 2026
09:31
Heterokaryon Technique for Analysis of Cell Type-specific Localization
Published on: March 11, 2011
Localization of a gene: the nucleolar organizer
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.]
|December 1, 1979
Abstract:
Nucleolus differentiates around the nucleolus organizer regions of the chromosomes or NORs. In the interphasic nucleoli the fibrillar centers are now considered as the NORs. The purpose of this editorial is to review the experimental data which allowed such identification. Our current concepts regarding this point result from three lines of evidence: 1) specific localization during nucleologenesis, 2) in situ hybridization with labeled ribosomal RNA or DNA, and 3) specific staining with silver.
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